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Deferoxamine Mesylate → N-[5-[[4-[5-[acetyl(hydroxy)amino]pentylamino]-4-oxo-butanoyl]-hydroxy-amino]pentyl]-N'-(5-aminopentyl)-N'-hydroxy-butanediamide; zinc
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Deferoxamine Mesylate | HCID 62881 | — |
| 反応物 | Zincchloride | HCID 3007855 | — |
| 生成物 | N-[5-[[4-[5-[acetyl(hydroxy)amino]pentylamino]-4-oxo-butanoyl]-hydroxy-amino]pentyl]-N'-(5-aminopentyl)-N'-hydroxy-butanediamide; zinc | HCID 473262 | — |
反応手順
10 mM solution of Desferal (Ciba-Geigy, Basle) is mixed with an equal volume of 10 mM solution of ZnCl2 (A. R. Aldrich Chemical Co., Inc.) solution, titrated to pH 7.4. The mixture is heated for 30 min. to 45° C., and cooled and the complex Zn/Desferrioxamine B is formed. The ratio Zn:Desferal is 1.0:1.0.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05075469 |
| 出典データセット | uspto-grants-1991_12 |
| ORD ID | ord-9b48318f39834b92aae0d2a02abc1227 |
| 出典メモ | uspto-grants-1991_12 |