HuagongsheHuagongshe Chemistry Print Report · For research reference only
1H-imidazole-2-carbaldehyde → HCID 178501368, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1H-imidazole-2-carbaldehyde | HCID 24955 | — |
| Reactant | Methyl L-phenylalaninate hydrochloride | HCID 75736 | — |
| Solvent | Dichloromethane ethyl acetate methanol | HCID 21901258 | — |
| Product | HCID 178501368 | HCID 178501368 | — |
Reaction Steps
N-(2-methylimidazolyl)-L-phenylalanine methyl ester was prepared from L-phenylalanine methyl ester hydrochloride (3.30 mmol) and 2-formyl-imidazole (3.63 mmol) utilizing the procedure of Example 9, first paragraph, to yield, after flash chromatography (3:50:50 v/v/v CH3OH/EtOAc/CH2Cl2 ; SiO2 gel), 0.55 g (65% yield) of pure product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05075451 |
| Source dataset | uspto-grants-1991_12 |
| ORD ID | ord-0330458a4f0e4b36b3a3f81829006f90 |
| Source note | uspto-grants-1991_12 |