HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-tert-Butylphenol → Rac-4-[2-(4-tert-butyl-phenoxy)-2-fluoro-acetylamino]-thiophene-3-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-tert-Butylphenol | HCID 7393 | — |
| Reactant | 4-(2-Chloro-2-fluoro-acetylamino)-thiophene-3-carboxylic acid methyl ester | HCID 68689462 | — |
| Product | Rac-4-[2-(4-tert-butyl-phenoxy)-2-fluoro-acetylamino]-thiophene-3-carboxylic acid | HCID 16068687 | — |
Reaction Steps
In analogy to Example 58, the title compound was prepared using 4-(2-chloro-2-fluoro-acetylamino)-thiophene-3-carboxylic acid methyl ester and 4-tert-butylphenol. MS (m/e): 350.3 (M−H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07732452B2 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-d2b7ab22b54244d1aaa331dd8619542f |
| Source note | uspto-grants-2010_06 |