1-(2-Pyrimidinyl)piperazine → HCID 14882741, compound

HRID 1461744Notes

Reaction equation

HRID 1461744 reaction equation
[Cl:1][CH2:2][CH2:3][N:4]1[CH2:9][CH2:8][CH:7]([C:10](=[O:18])[C:11]2[CH:16]=[CH:15][C:14]([F:17])=[CH:13][CH:12]=2)[CH2:6][CH2:5]1.[N:19]1[CH:24]=[CH:23][CH:22]=[N:21][C:20]=1[N:25]1[CH2:30][CH2:29][NH:28][CH2:27][CH2:26]1>>[ClH:1].[ClH:1].[F:17][C:14]1[CH:15]=[CH:16][C:11]([C:10]([CH:7]2[CH2:8][CH2:9][N:4]([CH2:3][CH2:2][N:28]3[CH2:29][CH2:30][N:25]([C:20]4[N:19]=[CH:24][CH:23]=[CH:22][N:21]=4)[CH2:26][CH2:27]3)[CH2:5][CH2:6]2)=[O:18])=[CH:12][CH:13]=1

Participants

3

Reactant 2

HCID 887471-(2-Pyrimidinyl)piperazineHCID 10516150Methanone, [1-(2-chloroethyl)-4-piperidinyl](4-fluorophenyl)-

Product 1

HCID 14882741HCID 14882741, compound

Procedure

This compound was prepared from 1-(2-chloroethyl)-4-(4-fluorobenzoyl)piperidine and 1-(2-pyrimidinyl) piperzine according to the process described in Example 3, Stage B.

Sources & evidence

ORD record
ord-355324c0d10e4054aa63183f126dfea1
Source dataset
uspto-grants-1991_12
Patent number
US05077288

Reaction notes

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