HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxalyl chloride → 4-Hexadecyloxyphenoxyacetic chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | [4-(Hexadecyloxy)phenoxy]acetic acid | HCID 9977851 | — |
| Catalyst | Dimethylformamide | HCID 6228 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 4-Hexadecyloxyphenoxyacetic chloride | HCID 10431724 | 100.6% |
Reaction Steps
A mixture of 13.2 g of [4-(hexadecyloxy)phenoxy]acetic acid, 6.4 g of oxalyl chloride, 225 ml of methylene chloride and 5 drops of N,N-dimethylformamide is stirred at ambient temperature for 17 hours. The solvent is evaporated to a residue which is dissolved in ether and filtered through diatomaceous earth. The filtrate is evaporated to give 13.9 g of the desired product as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05077409 |
| Source dataset | uspto-grants-1991_12 |
| ORD ID | ord-cf5a458d9acf4365903d8f4f879c28b3 |
| Source note | uspto-grants-1991_12 |