Isophorone → 3,3,5-Trimethylcyclohexanone

Participants

Reaction Conditions

Reaction Steps

2.2 kg of isophorone and 5 g of 5% palladium-on-carbon catalyst are added to a 3 liter autoclave which is fitted with heating means, cooling means and a stirrer. A hydrogen pressure of 8-10 atmospheres is now generated and the mixture is slowly warmed to 30°-35° C. Since the hydrogenation is exothermic, provision is made by cooling that a temperature of 50° C. is not exceeded. After completion of the hydrogen uptake (temperature drop), the catalyst is filtered off. There are thus obtained 2.2 kg of crude dihydroisophorone, which is uniform according to gas chromatography and which is used directly.

Provenance & Evidence