Methanol → 2-(Trifluoromethyl)-5,6,7,8-tetrahydroquinoline-6-carboxylic acid
Reaction equation
[CH3:21][OH:22].[F:1][C:2]([c:3]1[n:4][c:5]2[c:10]([cH:11][cH:12]1)[CH2:9][CH:8]([C:13](=[O:14])[O:15][CH3:16])[CH2:7][CH2:6]2)([F:17])[F:18].[Na+:20].[OH-:19]>>[F:1][C:2]([c:3]1[n:4][c:5]2[c:10]([cH:11][cH:12]1)[CH2:9][CH:8]([C:13](=[O:14])[OH:15])[CH2:7][CH2:6]2)([F:17])[F:18]Participants
5
Sources & evidence
- ORD record
- ord-e9f907c87d9c40f9a4298c4705f999fc
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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