HCID 70513844, compound → HCID 178439202, compound

HRID 1461980Notes

Reaction equation

HRID 1461980 reaction equation
[C:1]([C:3](=[CH:9][NH:10][C:11]1[C:16]([CH2:17][CH2:18][CH3:19])=[CH:15][CH:14]=[CH:13][N:12]=1)[C:4](OCC)=[O:5])#[N:2].[NH:20]1C(C2C(=O)N3C=CC=CC3=NC=2)=N[N:22]=[N:21]1>>[CH2:17]([C:16]1[C:11]2=[N:10][CH:9]=[C:3]([C:1]3[NH:2][N:22]=[N:21][N:20]=3)[C:4](=[O:5])[N:12]2[CH:13]=[CH:14][CH:15]=1)[CH2:18][CH3:19]

Participants

3

Reactant 2

HCID 70513844HCID 70513844, compoundHCID 178515422HCID 178515422, compound

Product 1

HCID 178439202HCID 178439202, compoundYield 27.6%

Procedure

The title compound (m.p. 269°-272° with decomposition, 27.6% yield) was prepared from ethyl 2-cyano-3-(3-n-propyl-2-pyridylamino)acrylate in a manner similar to that described for the preparation of 3-(1H-tetrazol-5-yl)-4H-pyrido[1,2-a]pyrimidin-4-one in Example 2 of U.S. Pat. No. 4,122,274.

Sources & evidence

ORD record
ord-4dc707a2a2fc40629281a968b3c9df96
Source dataset
uspto-grants-1984_07
Patent number
US04457932

Reaction notes

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