HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Propenoic acid, 2-cyano-3-ethoxy-, ethyl ester → Ethyl 2-cyano-3-(3-chloro-2-pyridylamino)acrylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Propenoic acid, 2-cyano-3-ethoxy-, ethyl ester | HCID 78943 | — |
| Reactant | 2-Amino-3-chloropyridine | HCID 693267 | — |
| Reactant | Ethyl 2-cyano-3-(5-n-butyl-2-pyridylamino)acrylate | HCID 70514903 | — |
| Product | Ethyl 2-cyano-3-(3-chloro-2-pyridylamino)acrylate | HCID 70515126 | 44% |
Reaction Steps
The title compound (m.p. 139.5°-141.5°, 44% yield) was prepared from 2-amino-3 -chloropyridine and ethyl ethoxymethylenecyanoacetate in a manner similar to that described for the preparation of ethyl 2-cyano-3-(5-n-butyl-2-pyridylamino)acrylate in Preparation D3 of U.S. Pat. No. 4,122,274.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04457932 |
| Source dataset | uspto-grants-1984_07 |
| ORD ID | ord-31438884dba449998bb09c1c720b0d56 |
| Source note | uspto-grants-1984_07 |