HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium → HCID 70466798, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium | HCID 3028194 | — |
| Reactant | HCID 70466324 | HCID 70466324 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 70466798 | HCID 70466798 | 99.5% |
Reaction Steps
9.0 g of 1α,2α-methylene-17β-(tetrahydropyran-2-yloxy)-5α-androstan-3-one is stirred in 90 ml of tetrahydrofuran with 10 g of lithium tri-tert-butoxyalanate for 2.5 hours at room temperature. The reaction solution is diluted with diethyl ether, washed with 2N sulfuric acid and water, dried, and evaporated, yielding as a residue 9.0 g of 1α,2α-methylene-17β-(tetrahydropyran-2-yloxy)-5α-androstan-3-ol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04457925 |
| Source dataset | uspto-grants-1984_07 |
| ORD ID | ord-e85f1d8e5b564440a2104593420aa960 |
| Source note | uspto-grants-1984_07 |