Morpholine → HCID 13345106, compound

HRID 1462028Notes

Reaction equation

HRID 1462028 reaction equation
[Br:1][CH:2]([CH3:6])[C:3](Cl)=[O:4].[NH:7]1[CH2:12][CH2:11][O:10][CH2:9][CH2:8]1>C1C=CC=CC=1.CO>[Br:1][CH:2]([CH3:6])[C:3]([N:7]1[CH2:12][CH2:11][O:10][CH2:9][CH2:8]1)=[O:4]

Participants

4

Reactant 2

HCID 8083MorpholineHCID 979802-Bromopropanoyl chloride

Product 1

HCID 13345106HCID 13345106, compound

Reagents, catalysts & solvents 1

HCID 21927730Benzene methanolSolvent

Procedure

This compound is prepared by reaction of 2-bromopropionylchloride with morpholine under the experimental conditions of Example 10: b.p. 115°-120° C. (0.1-0.2 mm); Rf=0.52 (C6H6 -MeOH 80:20); IR (neat) νmax: 2860, 1660, 1470, 1440, 1280, 1260, 1125, 1040 cm-1. The product is very irritating to the skin and mucosae.

Sources & evidence

ORD record
ord-de5a1ba77a4d439eab399045347b8352
Source dataset
uspto-grants-1984_07
Patent number
US04457931

Reaction notes

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