Phenyl isocyanate → HCID 14772183, compound

HRID 1462188Notes

Reaction equation

HRID 1462188 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:9]2[N:13]=[C:12]([C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=3[CH3:20])[NH:11][N:10]=2)[CH:6]=[CH:7][CH:8]=1.[C:21]1([N:27]=[C:28]=[O:29])[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1>C(#N)C>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:9]2[N:13]=[C:12]([C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=3[CH3:20])[N:11]([C:28](=[O:29])[NH:27][C:21]3[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=3)[N:10]=2)[CH:6]=[CH:7][CH:8]=1

Participants

4

Reactant 2

HCID 7672Phenyl isocyanateHCID 134253s-Triazole, 5-(m-methoxyphenyl)-3-(o-tolyl)-

Product 1

HCID 14772183HCID 14772183, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

A solution of 0.53 g (0.002 mole) of 3-(3-methoxyphenyl)-5-(2-methylphenyl)-1H-1,2,4-triazole and 0.22 ml. (0.002 mole) of phenylisocyanate in 5 ml of acetonitrile was strred for 7 hours at room temperature and, subsequently, it was left standing overnight. The solvent was evaporated off and the obtained residue was first taken up with hexane, then, after separating the liquid and the solid phase by decantation, it was recrystallized from acetonitrile. Yield: 0.25 g of the title compound. M.p. 123°-125° C. Δδ=-0.18.

Workup

  1. waitsubsequently, it was left
  2. customThe solvent was evaporated off
  3. customafter separating the liquid
  4. customthe solid phase by decantation, it was recrystallized from acetonitrile

Sources & evidence

ORD record
ord-88162e693bed48b29de7a211b5465499
Source dataset
uspto-grants-1984_07
Patent number
US04459302

Reaction notes

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