Ethanethiol → HCID 13336875, compound

HRID 1462290Notes

Reaction equation

HRID 1462290 reaction equation
[C:1]([C:3]1[C:8]([C:9]#[N:10])=[N:7][C:6](Cl)=[C:5]([CH3:12])[N:4]=1)#[N:2].[CH2:13]([SH:15])[CH3:14].[OH-].[Na+]>>[C:1]([C:3]1[C:8]([C:9]#[N:10])=[N:7][C:6]([S:15][CH2:13][CH3:14])=[C:5]([CH3:12])[N:4]=1)#[N:2]

Participants

4

Reactant 3

HCID 6343EthanethiolHCID 14798Sodium HydroxideHCID 129071985-Chloro-6-methylpyrazine-2,3-dicarbonitrile

Product 1

HCID 13336875HCID 13336875, compoundYield 45%

Procedure

2,3-Dicyano-5-chloro-6-methylpyrazine (1.79 g; 0.01 mole), 0.62 g (0.01 mole) of ethanethiol and 0.40 g (0.01 mole) of sodium hydroxide were worked up in the same way as in Example 8. Recrystallization from ethanol afforded 0.91 g (yield 45%) of 2,3-dicyano-5-ethylthio-6-methylpyrazine.

Workup

  1. customRecrystallization from ethanol

Sources & evidence

ORD record
ord-8e34c42eb7994a84976a28b6aeb1d464
Source dataset
uspto-grants-1984_07
Patent number
US04460403

Reaction notes

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