HuagongsheHuagongshe Chemistry Print Report · For research reference only
(+)-Styrene oxide → HCID 10363976, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (+)-Styrene oxide | HCID 114705 | — |
| Reactant | 5-[2-(Benzylamino)-ethoxy]-salicylamide | HCID 13754419 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | HCID 10363976 | HCID 10363976 | — |
Reaction Steps
A solution of 7.2 g of (R)-2-phenyl-oxirane and 14.3 g of 5-(2-benzylamino-ethoxy)-salicylamide in 100 ml of isopropanol is refluxed for 22-24 hours. The solution is concentrated by evaporation to yield (R)-α-[N-benzyl-N-[2-(3-carbamoyl-4-hydroxy-phenoxy)-ethyl]-aminomethyl]-benzyl alcohol, which is further processed in this form.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04460580 |
| Source dataset | uspto-grants-1984_07 |
| ORD ID | ord-d300352329cd4b4e94b1c5e9a6fe00c3 |
| Source note | uspto-grants-1984_07 |