HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → 2-[2-(4-Chlorophenyl)-5-(3-thienyl)-4-oxazolyl]acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | Ethyl 2-[2-(4-chlorophenyl)-5-(3-thienyl)-4-oxazolyl]acetate | HCID 13105437 | — |
| Solvent | Water | HCID 962 | — |
| Product | 2-[2-(4-Chlorophenyl)-5-(3-thienyl)-4-oxazolyl]acetic acid | HCID 13105440 | 89% |
Reaction Steps
6 g of ethyl 2-[2-(4-chlorophenyl)-5-(3-thienyl)-4-oxazolyl]acetate, 150 ml of methanol, 30 ml of water and 2.2 g of potassium hydroxide are treated in the same manner as described in Example 8. 4.9 g of 2-[2-(4-chlorophenyl)-5-(3-thienyl)-4-oxazolyl]acetic acid are thereby obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04460596 |
| Source dataset | uspto-grants-1984_07 |
| ORD ID | ord-ddfcad6f82624db9bd42f25ab156cdaa |
| Source note | uspto-grants-1984_07 |