HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoyl chloride → alpha-N-benzoylamino-2-acetylthiophene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoyl chloride | HCID 7412 | — |
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Reactant | 2-Amino-1-(thiophen-2-yl)ethan-1-one hydrochloride | HCID 12609833 | — |
| Product | alpha-N-benzoylamino-2-acetylthiophene | HCID 13105421 | 94% |
Reaction Steps
5 g of N-[(2-thienylcarbonyl)methyl]amine hydrochloride, 10 g of sodium bicarbonate and 3.9 g of benzoyl chloride are treated in the same manner as described in Preparation 1-(3). 6.4 g of N-benzoyl-N-[(2-thienylcarbonyl)methyl]amine are thereby obtained. Yield: 93.3%
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04460596 |
| Source dataset | uspto-grants-1984_07 |
| ORD ID | ord-faf90c3ce25044c7bb039e1ab8eafe3e |
| Source note | uspto-grants-1984_07 |