HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,1'-Carbonyldiimidazole → 11H-imidazo[1,2-c][1,3]benzodiazepin-5(6H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| Reactant | 2-[(1H-Imidazol-2-yl)methyl]aniline | HCID 13344903 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 11H-imidazo[1,2-c][1,3]benzodiazepin-5(6H)-one | HCID 13344922 | — |
Reaction Steps
Alternately, 0.75 g of 1,1'-carbonyldiimidazole is added at once to a suspension of 0.79 g of 2-(2-aminobenzyl)imidazole in 38 ml of methylene chloride and the mixture is stirred at room temperature overnight. The resulting precipitate is collected and recrystallized from methylene chloride to give the crude 11H-imidazo[1,2-c][1,3]benzodiazepin-5(6H)-one, m.p. 238°-40°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04460587 |
| Source dataset | uspto-grants-1984_07 |
| ORD ID | ord-0bd503accad743658d621b2f23b73232 |
| Source note | uspto-grants-1984_07 |