Methylhydrazine → HCID 56624470, compound

HRID 1462498Notes

Reaction equation

HRID 1462498 reaction equation
C1(=O)[N:5]([CH:6]2[CH2:11][S:10][C@H:9]([C:12]3[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=3)[N:8]([CH2:18][C:19]([O:21][CH2:22][CH2:23][Si:24]([CH3:27])([CH3:26])[CH3:25])=[O:20])[C:7]2=[O:28])C(=O)C2=CC=CC=C12.CNN>C(Cl)(Cl)Cl>[NH2:5][CH:6]1[CH2:11][S:10][C@H:9]([C:12]2[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=2)[N:8]([CH2:18][C:19]([O:21][CH2:22][CH2:23][Si:24]([CH3:26])([CH3:25])[CH3:27])=[O:20])[C:7]1=[O:28]

Participants

4

Reactant 2

HCID 6061MethylhydrazineHCID 56636303HCID 56636303, compound

Product 1

HCID 56624470HCID 56624470, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

A solution of the trimethylsilylethyl ester product from part (a) in dry chloroform is treated with N-methylhydrazine according to the procedure of Example 1(d) to give (R)-dihydro-5-amino-4-oxo-2-phenyl-2H-1,3-thiazine-3(4H)-acetic acid, trimethylsilylethyl ester.

Sources & evidence

ORD record
ord-0c68fc398c7f4ba5a2d7d751a49907f0
Source dataset
uspto-grants-1984_07
Patent number
US04460579

Reaction notes

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