Azelaic Acid → Methyl 8-bromooctanoate

HRID 1462618Notes

Reaction equation

[C:1](O)(=O)CCCCCCCC(O)=O.[Br:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][C:22]([OH:24])=[O:23]>>[Br:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][C:22]([O:24][CH3:1])=[O:23]

Participants

Reactant 2

HCID 2266Azelaic Acid

HCID 5482758-Bromooctanoic acid

Product 1

HCID 11107373Methyl 8-bromooctanoate

Procedure

Methyl 8-bromooctanoate was prepared from azelaic acid essentially as described in U.S. Pat. No. 3,852,419, or by direct esterification of 8-bromooctanoic acid as follows:

Sources & evidence

ORD record: ord-b8877ef69c5d4de8b6887ee24789780c
Source dataset: uspto-grants-1984_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04460777

Reaction notes

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