HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → 1-[7-(N-methylcarbamoyl)heptyl]-3-methyl-2-(3-pyridyl)indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | 1-(7-Methoxycarbonylheptyl)-3-methyl-2-(3-pyridyl)indole | HCID 13362086 | — |
| Solvent | 1-Butanol | HCID 263 | — |
| Product | 1-[7-(N-methylcarbamoyl)heptyl]-3-methyl-2-(3-pyridyl)indole | HCID 20441669 | — |
Reaction Steps
A solution of 4 g of 1-(7-methoxycarbonylheptyl)-3-methyl-2-(3-pyridyl)indole in 40 ml of n-butanol is saturated with methylamine and heated on a steam bath in a pressure bottle for 3 days. The reaction mixture is evaporated to dryness and the product is crystallized to yield the 1-[7-(N-methylcarbamoyl)heptyl]-3-methyl-2-(3-pyridyl)indole.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04460777 |
| Source dataset | uspto-grants-1984_07 |
| ORD ID | ord-0510bc3a236f4f9881b1550649312aac |
| Source note | uspto-grants-1984_07 |