HCID 53693383, compound → HCID 13102421, compound

Participants

Reaction Steps

57 g (0.256 mol) of 1-chloro-3,3-dimethyl-2-phenoxy-1,4-pentadiene (see Example A1(a)) are warmed to 40° C. in a mixture of 250 ml of formic acid and 50 ml of concentrated hydrochloric acid, during the course of 1 hour. The mixture is then diluted with 400 ml of methylene chloride and ice, and is three times extracted by shaking with 2N sodium hydroxide solution. After drying the methylene chloride phase over sodium sulphate, the solvent is removed. 36 g of product (96% of theory) remain, and this product is distilled. 32.2 g (86% of theory) of 1-chloro-3,3-dimethyl-pent-4-en-2-one are obtained at a boiling point of 81°-84° C./24 mm Hg.

Provenance & Evidence