HCID 20452409, compound → HCID 20452406, compound

HRID 1462937Notes

Reaction equation

HRID 1462937 reaction equation
[CH2:1]([O:8][C:9]1[CH:10]=[C:11]([CH:21]=[CH:22][C:23]=1[O:24][CH3:25])[C:12]([NH:14][CH2:15][CH2:16][CH2:17][C:18](O)=[O:19])=[O:13])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>C(OC(=O)C)(=O)C>[CH2:1]([O:8][C:9]1[CH:10]=[C:11]([CH:21]=[CH:22][C:23]=1[O:24][CH3:25])[C:12]([N:14]1[CH2:15][CH2:16][CH2:17][C:18]1=[O:19])=[O:13])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 1

HCID 20452409HCID 20452409, compound

Product 1

HCID 20452406HCID 20452406, compound

Reagents, catalysts & solvents 1

HCID 7918Acetic AnhydrideSolvent

Procedure

2.0 g of 4-[(3-benzyloxy-4-methoxybenzoyl)amino]butyric acid are heated to reflux for 1 hour in 10 ml of acetic acid anhydride. After evaporation of the acetic acid anhydride, the residue is stirred at room temperature with diethyl ether. The mixture is filtered and the filter residue is washed with diethyl ether. There is obtained 1-(3-benzyloxy-4-methoxybenzoyl)-2-pyrrolidinone of melting point 92°-92° C.

Workup

  1. customAfter evaporation of the acetic acid anhydride
  2. filtrationThe mixture is filtered
  3. washthe filter residue is washed with diethyl ether

Sources & evidence

ORD record
ord-3be0b0964e7542e7b9ebb7ae002aa14d
Source dataset
uspto-grants-1984_07
Patent number
US04461906

Reaction notes

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