HCID 20452406, compound → 2-Pyrrolidinone, 1-(3-hydroxy-4-methoxybenzoyl)-

HRID 1462938Notes

Reaction equation

HRID 1462938 reaction equation
C([O:8][C:9]1[CH:10]=[C:11]([CH:20]=[CH:21][C:22]=1[O:23][CH3:24])[C:12]([N:14]1[CH2:18][CH2:17][CH2:16][C:15]1=[O:19])=[O:13])C1C=CC=CC=1>CO.[Pd]>[OH:8][C:9]1[CH:10]=[C:11]([CH:20]=[CH:21][C:22]=1[O:23][CH3:24])[C:12]([N:14]1[CH2:18][CH2:17][CH2:16][C:15]1=[O:19])=[O:13]

Participants

4

Reactant 1

HCID 20452406HCID 20452406, compound

Product 1

HCID 30608052-Pyrrolidinone, 1-(3-hydroxy-4-methoxybenzoyl)-

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

2.0 g of 1-(3-benzyloxy-4-methoxybenzoyl)-2-pyrrolidinone are hydrogenated in 60 ml of absolute methanol with 0.5 g of 5% palladium/carbon under atmospheric pressure and at room temperature. The catalyst is filtered off and the filtrate is concentrated and stirred with diethyl ether. After filtration, there is obtained 1-(3-hydroxy-4-methoxybenzoyl)-2-pyrrolidinone of melting point 123°-125° C.

Workup

  1. filtrationThe catalyst is filtered off
  2. concentrationthe filtrate is concentrated
  3. filtrationAfter filtration

Sources & evidence

ORD record
ord-d8bb651f64cb44d5a17224e3a0e8bb5d
Source dataset
uspto-grants-1984_07
Patent number
US04461906

Reaction notes

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