1-(Trimethylsilyl)pyrrolidin-2-one → HCID 20452407, compound

HRID 1462945Notes

Reaction equation

HRID 1462945 reaction equation
[CH2:1]([O:8][C:9]1[CH:10]=[C:11]([CH:15]=[CH:16][C:17]=1[O:18][CH3:19])[C:12](Cl)=[O:13])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C[Si](C)(C)[N:22]1[CH2:26][CH2:25][CH2:24][C:23]1=[O:27].C[O:31]C1C=CC(C(N2C(=O)C(O)CC2)=O)=CC=1>>[C:1]([O:8][C:9]1[CH:10]=[C:11]([CH:15]=[CH:16][C:17]=1[O:18][CH3:19])[C:12]([N:22]1[CH2:26][CH2:25][CH2:24][C:23]1=[O:27])=[O:13])(=[O:31])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 3

HCID 844611-(Trimethylsilyl)pyrrolidin-2-oneHCID 30608043-Hydroxy-1-(4-methoxybenzoyl)pyrrolidin-2-oneHCID 109677953-Benzyloxy-4-methoxybenzoyl chloride

Product 1

HCID 20452407HCID 20452407, compound

Procedure

By heating equimolar amounts of 3-benzyloxy-4-methoxybenzoyl chloride and 1-trimethylsilyl-2-pyrrolidinone in an oil-bath of 100° C. in analogy to the procedure described in paragraph (b) of Example 9 there is obtained 1-(3-benzoyloxy-4-methoxybenzoyl)-2-pyrrolidinone. After stirring in diethyl ether and recrystallisation from ethyl acetate/n-hexane (3:1), the substance melts at 90.5°-91° C.

Sources & evidence

ORD record
ord-33259b20381143b5a41316d7dc7a5d35
Source dataset
uspto-grants-1984_07
Patent number
US04461906

Reaction notes

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