HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 4478874, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 4'-Methoxyacetophenone | HCID 7476 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | 5-Bromosalicylaldehyde | HCID 72863 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 4478874 | HCID 4478874 | — |
Reaction Steps
5-Bromosalicylaldehyde (20.1 g) and p-methoxyacetophenone (15.0 g) were dissolved in ethanol (80 ml) and a solution of potassium hydroxide (26.5 g) in water (40 ml) was added, with cooling. The reaction mixture was allowed to stand overnight, and then was acidified by addition to excess hydrochloric acid. The precipitated 5-bromo-2-hydroxy.4'-methoxychalcone was filtered off, washed with water, and recrystallised from ethanol, 27.5 g, m.p. 177°-179°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04461907 |
| Source dataset | uspto-grants-1984_07 |
| ORD ID | ord-bf41aa3a2b444246980382d3d77d859b |
| Source note | uspto-grants-1984_07 |