Hydrochloric Acid → [4-(Hydroxyamino)phenyl]boronic acid--hydrogen chloride (1/1)

Participants

Reaction Steps

Employing the procedure of Example II, 1.1 gms of 4-nitrophenylboronic acid was hydrogenated at 42 psi in 50 ml of methanol containing 0.7 ml of conc. HCl on a Parr shaker hydrogenation apparatus for 3 hours using palladium on carbon as catalyst. After filtering, the filtrate was concentrated yielding 0.91 gms of a white-powdery solid having a melting point of 200°-205° C. (decomposition).

Provenance & Evidence