Sulfuric Acid → HCID 20450693, compound

Participants

Reaction Steps

A mixture of 16.8 g of 4-hydroxy-3-(hydroxymethyl)-benzoic acid, 1000 ml of benzene, 15.0 g of caproaldehyde and 0.36 ml of concentrated sulphuric acid is boiled for 5 hours while stirring under a water separator. After cooling, the mixture is filtered. The filtrate is concentrated and the residue is boiled up with hexane. The insoluble material is dissolved in ether/hexane and stirred up in the cold with active carbon. The mixture is filtered, the filtrate is evaporated and the residue is boiled with isopropyl ether. There are obtained 11.7 g of beige colored 2-pentyl-1,3-benzodioxan-6-carboxylic acid; m.p. 148° C.

Provenance & Evidence