Methyl Isocyanate → Carbofuran

HRID 1463119Notes

Reaction equation

HRID 1463119 reaction equation
[CH3:1][C:2]1([CH3:12])[O:6][C:5]2[C:7]([OH:11])=[CH:8][CH:9]=[CH:10][C:4]=2[CH2:3]1.[CH3:13][N:14]=[C:15]=[O:16]>>[CH3:1][C:2]1([CH3:12])[O:6][C:5]2[C:4](=[CH:10][CH:9]=[CH:8][C:7]=2[O:11][C:15]([NH:14][CH3:13])=[O:16])[CH2:3]1

Participants

3

Reactant 2

HCID 12228Methyl IsocyanateHCID 152782,3-Dihydro-2,2-dimethyl-7-benzofuranol

Product 1

HCID 2566Carbofuran

Procedure

The carbofuran phenol from Examples 3 and 4 is then reacted with methyl isocyanate in the presence of a tertiary amine catalyst to give carbofuran (2,3-dihydro-2,2-dimethyl-7-benzofuranyl-N-methyl carbamate).

Sources & evidence

ORD record
ord-8bcd8939529f4d03a5efb5b018d5f147
Source dataset
uspto-grants-1984_07
Patent number
US04463184

Reaction notes

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