反应详情

The diphenylmethyl 3-acetoxymethyl-7-(4-acetylaminobenzimidazol-2-yl)aminoceph-3-em-4-carboxylate used as starting material may be obtained by reaction of the corresponding 4-aminobenzimidazole derivative in dry methylene chloride with excess acetyl chloride and purifying the product by chromatography on silica using CH2Cl2 /MeOH/HOAc 97:1:2 v/v/v as eluant.