Acetic Anhydride → HCID 53661794, compound

HRID 1463204Notes

Reaction equation

HRID 1463204 reaction equation
[CH2:1]([N:8]1[C:12]2=[CH:13][CH:14]=[C:15]([C:20]([OH:22])=[O:21])[C:16]([C:17](O)=[O:18])=[C:11]2[N:10]=[C:9]1[CH3:23])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C(OC(=O)C)(=O)C>>[CH2:1]([N:8]1[C:12]2=[CH:13][CH:14]=[C:15]3[C:20](=[O:21])[O:22][C:17](=[O:18])[C:16]3=[C:11]2[N:10]=[C:9]1[CH3:23])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 7918Acetic AnhydrideHCID 22402967HCID 22402967, compound

Product 1

HCID 53661794HCID 53661794, compoundYield 91.1%

Conditions

Temperature
0 °C

Procedure

A mixture of the 1-benzyl-2-methyl-4,5-benzimidazoledicarboxylic acid (4.40 g, 14.2 mmol) and acetic anhydride is stirred for 5 hours at reflux temperature, cooled to 0° C. and filtered to give the title product as a pale yellow solid (3.78 g, 91.1%), identified by 1HNMR spectrography.

Workup

  1. temperatureat reflux temperature
  2. filtrationfiltered

Sources & evidence

ORD record
ord-555a8e91c2bd4e41b010f4bd4dd1a3cf
Source dataset
uspto-grants-1994_04
Patent number
US05300479

Reaction notes

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