Pyridine → 4-Phenylsulfonyl-1-acetoxybenzene

HRID 1463277Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1463277
[C:1]1([S:7]([C:10]2[CH:15]=[CH:14][C:13]([OH:16])=[CH:12][CH:11]=2)(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.N1C=CC=CC=1.[C:23](Cl)(=[O:25])[CH3:24]>C(Cl)Cl>[C:1]1([S:7]([C:10]2[CH:11]=[CH:12][C:13]([O:16][C:23](=[O:25])[CH3:24])=[CH:14][CH:15]=2)(=[O:8])=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Komponenten

5

Edukt 3

HCID 1049PyridineHCID 6367Acetyl chlorideHCID 3438044-(Benzenesulfonyl)phenol

Produkt 1

HCID 121495774-Phenylsulfonyl-1-acetoxybenzene

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel

Versuchsvorschrift

In 150 ml of CH2Cl2 were dissolved 23 g of the compound obtained in step 2; and, 12.9 ml of pyridine and 7.8 ml of acetyl chloride was slowly added at room temperature thereto. The reaction solution was washed with 0.2N HCl and with saturated NaHCO3 aqueous solution, dried over Na2SO4 and concentrated under reduced pressure to obtain residue, which was used for subsequent reaction without further purification.

Aufarbeitung

  1. washThe reaction solution was washed with 0.2N HCl and with saturated NaHCO3 aqueous solution
  2. dry with materialdried over Na2SO4
  3. concentrationconcentrated under reduced pressure
  4. customto obtain residue, which
  5. customwas used for subsequent reaction without further purification

Quellen und Nachweise

ORD-Eintrag
ord-201abcf7a0314b56957a18fcd9076221
Quelldatensatz
uspto-grants-1994_04
Patentnummer
US05300511

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