3-Pyridinepropanol → HCID 12904541, compound

HRID 1463369Notes

Reaction equation

HRID 1463369 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][OH:12])[CH:2]=1.N1C=CC=C(CCCO)C=1>CO.C(Cl)(Cl)Cl>[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH2:7][CH2:8][CH2:9][CH2:10][CH:11]=[O:12])[CH:2]=1

Participants

5

Reactant 2

HCID 178613-PyridinepropanolHCID 6428103-PYRIDINEPENTANOL

Product 1

HCID 12904541HCID 12904541, compoundYield 96%

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 6212ChloroformSolvent

Procedure

Utilising the procedure described in example 10(a) employing 5-(3-pyridyl)-1-pentanol in lieu of 3-(3-pyridyl)-1-propanol gave after purification by column chromatography (flash silica gel, 5% methanol in chloroform) 5-(3-pyridyl)-1-pentanal (96% yield).

Workup

  1. customgave

Sources & evidence

ORD record
ord-525563d2894049f88acd584cdc3ef661
Source dataset
uspto-grants-1994_04
Patent number
US05300524

Reaction notes

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