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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1463393Generated: October 26, 2026

Gamma-Butyrolactone → 8-Bromo-2,3,4,5-tetrahydrobenzo[b]oxepine

https://huagongshe.com/reaction/1463393

Reaction equation

Participants

RoleNameHCIDCharge
ReactantGamma-ButyrolactoneHCID 7302—
Reactant3-BromophenolHCID 11563—
Product8-Bromo-2,3,4,5-tetrahydrobenzo[b]oxepineHCID 19935534—

Reaction Steps

m-Bromophenol was reacted with γ-butyrolactone in analogy to Example 17, paragraphs B, C and D, to give 8-bromo-2,3,4,5-tetrahydro-1-benzoxepine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05300522
Source datasetuspto-grants-1994_04
ORD IDord-b2fa1be7269d4ec9b9d454b11ebcb1ed
Source noteuspto-grants-1994_04