Pyridine → HCID 57077212, compound

Participants

Reaction Steps

The diastereomeric mixture of Example 2 (444 mg, 0.793 mmol) in anhydrous THF (4 mL) was treated with HF/pyridine (4.4M, 1.80 mL, 7.93 mmol) at room temperature for 5 days. Quench and work up as in the above Example 5, followed by chromatography (40% ethyl acetate/hexane) gave title compound as a white solid. (139 mg, 54%).

Provenance & Evidence