Fluorene → HCID 15296112, compound

Participants

Reaction Steps

The title compound was prepared following the procedure described in Example 5 from 10.0 mmole of fluorene, 22.0 mmole of 3-picolylchloride hydrochloride, 2.0 mmole of cetyl tri-n-butyl phosphonium bromide, 20 ml of 50% sodium hydroxide and 40 ml of toluene by reaction at 50° for 6 hrs. The material was chromatographed (silica, CH2Cl2 /MeOH,95:5) to yield 2.6 g (70%), m.p. 137°-138°. δ: 3.41(s,4H), 6.71-6.97(m,4H), 7.17-7.35(tt,6H), 7.50-7.54(d,J=6.9 Hz, 2H), 7.91(s,2H), 8.12-8.15(d,J=5.4 Hz,2H). HRMS calculated for C25H20N2 : 348.1632 Found: 348.1626

Provenance & Evidence