Glycine → N-{4,6-Bis[N-(1-cyclohexyloxy-2,2,6,6-tetramethylpiperidin-4-yl)butylamino]-1,3,5-triazin-2-yl}glycine

HRID 1463714Notes

Reaction equation

HRID 1463714 reaction equation
Cl[C:2]1[N:7]=[C:6]([NH:8][CH2:9][CH2:10][CH2:11][CH2:12][CH:13]2[CH2:18][C:17]([CH3:20])([CH3:19])[N:16]([O:21][CH:22]3[CH2:27][CH2:26][CH2:25][CH2:24][CH2:23]3)[C:15]([CH3:29])([CH3:28])[CH2:14]2)[N:5]=[C:4]([NH:30][CH2:31][CH2:32][CH2:33][CH2:34][CH:35]2[CH2:40][C:39]([CH3:42])([CH3:41])[N:38]([O:43][CH:44]3[CH2:49][CH2:48][CH2:47][CH2:46][CH2:45]3)[C:37]([CH3:51])([CH3:50])[CH2:36]2)[N:3]=1.[NH2:52][CH2:53][C:54]([OH:56])=[O:55]>>[CH:44]1([O:43][N:38]2[C:37]([CH3:51])([CH3:50])[CH2:36][CH:35]([CH2:34][CH2:33][CH2:32][CH2:31][NH:30][C:4]3[N:5]=[C:6]([NH:8][CH2:9][CH2:10][CH2:11][CH2:12][CH:13]4[CH2:14][C:15]([CH3:28])([CH3:29])[N:16]([O:21][CH:22]5[CH2:23][CH2:24][CH2:25][CH2:26][CH2:27]5)[C:17]([CH3:19])([CH3:20])[CH2:18]4)[N:7]=[C:2]([NH:52][CH2:53][C:54]([OH:56])=[O:55])[N:3]=3)[CH2:40][C:39]2([CH3:41])[CH3:42])[CH2:45][CH2:46][CH2:47][CH2:48][CH2:49]1

Participants

3

Reactant 2

HCID 750GlycineHCID 225076382,4-Bis[(1-cyclohexyloxy-2,2,6,6-tetramethylpiperidin-4-yl)butylamino]-6-chloro-s-triazine

Product 1

HCID 54282857N-{4,6-Bis[N-(1-cyclohexyloxy-2,2,6,6-tetramethylpiperidin-4-yl)butylamino]-1,3,5-triazin-2-yl}glycine

Procedure

The title compound is prepared from the reaction of 2-chloro-4,6-bis[N-(1-cyclohexyloxy-2,2,6,6-tetramethylpiperidin-4-yl)butylamino]-1,3,5-triazine and glycine according to the procedure of Example 15.

Sources & evidence

ORD record
ord-98f19260bcce4430aebc07544b78cceb
Source dataset
uspto-grants-1994_04
Patent number
US05300544

Reaction notes

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