HCID 10846087, compound → HCID 85199613, compound

Participants

Reaction Conditions

Reaction Steps

3.9 g of diamine [10] was dissolved in 90 ml methanol and cooled to 0° C., after which 6.5 g of 2-chloro-2-methyl-3-nitrosobutane were added with agitation. After heating to room temperature the mixture was agitated for two hours, boiled with reflux for a further two hours, the solvent was removed and the remaining solid was dissolved in water. The mixture was neutralised with sodium hydrogen carbonate and concentrated and the remaining precipitate was re-crystallised from ethanol.

Provenance & Evidence