化工社化工社 化学情報印刷レポート · 研究参考用
Methanol → N-(1-deoxyfructopyranos-1-yl)-D-isoleucine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methanol | HCID 887 | — |
| 反応物 | D-Isoleucine | HCID 76551 | — |
| 反応物 | (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal | HCID 107526 | — |
| 溶媒 | Pyridine | HCID 1049 | — |
| 生成物 | N-(1-deoxyfructopyranos-1-yl)-D-isoleucine | HCID 86747745 | 49.2% |
反応手順
A dry mixture of 40 ml of methanol and 10 ml of pyridine was added to 100 mg of dry D-isoleucine together with 300 mg of anhydrous glucose, and reaction and purification were carried out as described in Example 9, but making use of smaller-volume chromatography columns. Crystallization of the final product yielded 110 mg of N-(1-deoxyfructopyranos-1-yl)-D-isoleucine. Melting point 142°-144° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05302582 |
| 出典データセット | uspto-grants-1994_04 |
| ORD ID | ord-811538b30e2940988f965e6fd7175727 |
| 出典メモ | uspto-grants-1994_04 |