反应详情

A suspension of the foregoing nitro compound (14.8 g, 48 mmol) in ethanol (240 ml) was hydrogenated over 10% palladium on carbon (1.4 g) at 45 psi for 1.5 hours. The reaction mixture was filtered then evaporated and the crude product recrystallised from hot ethanol to afford 3-(phenylsulphonylaminocarbonyl)aniline (10.57 g, 80%) as a colourless crystalline solid, mp 138° C. Rf=0.42 in dichloromethane/methanol (9:1) on silica plates.

1. filtrationThe reaction mixture was filtered
2. customthen evaporated
3. customthe crude product recrystallised from hot ethanol