Hydrazine → 4-(Morpholin-4-yl)butan-1-amine

HRID 1463798Notes

Reaction equation

HRID 1463798 reaction equation
[NH2:1]N.[N:3]1([CH2:9][CH2:10][CH2:11][CH2:12]C2C=CC=C3C(NC(=O)C=23)=O)[CH2:8][CH2:7][O:6][CH2:5][CH2:4]1>CO>[N:3]1([CH2:9][CH2:10][CH2:11][CH2:12][NH2:1])[CH2:4][CH2:5][O:6][CH2:7][CH2:8]1

Participants

4

Reactant 2

HCID 9321HydrazineHCID 220025214-Morpholinylbutylphthalimide

Product 1

HCID 2336114-(Morpholin-4-yl)butan-1-amine

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Hydrazine (aqueous solution at 35% by wt.) (0.15 ml; 1.6 mmoles) was added to 4-morpholinylbutylphthalimide (231 mg; 0.8 mmoles) in methanol (5 ml) and the resulting solution was refluxed. Reaction times and process as per Example 1.

Workup

  1. temperaturethe resulting solution was refluxed
  2. customReaction times and process as per Example 1

Sources & evidence

ORD record
ord-d4eac5790f2e4025960d08d0b535aae2
Source dataset
uspto-grants-1994_04
Patent number
US05302593

Reaction notes

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