Hydrazine → (5-Morpholin-4-ylpentyl)amine

HRID 1463800Notes

Reaction equation

HRID 1463800 reaction equation
[NH2:1]N.[N:3]1([CH2:9][CH2:10][CH2:11][CH2:12][CH2:13]C2C=CC=C3C(NC(=O)C=23)=O)[CH2:8][CH2:7][O:6][CH2:5][CH2:4]1>CO>[N:3]1([CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][NH2:1])[CH2:4][CH2:5][O:6][CH2:7][CH2:8]1

Participants

4

Reactant 2

HCID 9321HydrazineHCID 1317183825-Morpholinylpentylphthalimide

Product 1

HCID 7138467(5-Morpholin-4-ylpentyl)amine

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Hydrazine (aqueous solution at 35% by wt.) (0.15 ml; 1.6 mmoles) was added to 5-morpholinylpentylphthalimide (242 mg; 0.8 mmoles) in methanol (5 ml) and the resulting solution was refluxed. Reaction times and process as per Example 1.

Workup

  1. temperaturethe resulting solution was refluxed
  2. customReaction times and process as per Example 1

Sources & evidence

ORD record
ord-d1a145ba03bc4ca08837b23cf7b5fdff
Source dataset
uspto-grants-1994_04
Patent number
US05302593

Reaction notes

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