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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1463816Generated: November 3, 2026

1-Methylpiperazine → 4-(N-methylpiperazinyl)butylphthalimide

https://huagongshe.com/reaction/1463816

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-MethylpiperazineHCID 53167—
Reactant4-BromoethylphthalimideHCID 54159740—
SolventDiethyl EtherHCID 3283—
Product4-(N-methylpiperazinyl)butylphthalimideHCID 53826388—

Reaction Steps

4-Bromoethylphthalimide (564 mg; 2.0 mmoles) and N-methylpiperazine (0.44 ml; 4.0 mmoles) were dissolved in anhydrous ethyl ether (5 ml). Reaction times and process as per Example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05302593
Source datasetuspto-grants-1994_04
ORD IDord-63247b05e37848bfb8ebc8f8396868d1
Source noteuspto-grants-1994_04