Hydrazine → 8-(N-methylpiperazinyl)octylamine

HRID 1463820Notes

Reaction equation

HRID 1463820 reaction equation
[NH2:1]N.[CH3:3][N:4]1[CH2:9][CH2:8][NH:7][CH2:6][CH:5]1[CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17]C1C=CC=C2C(NC(=O)C=12)=O>CO>[CH3:3][N:4]1[CH2:9][CH2:8][NH:7][CH2:6][CH:5]1[CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][NH2:1]

Participants

4

Reactant 2

HCID 9321HydrazineHCID 538031688-(N-methylpiperazinyl)octylphthalimide

Product 1

HCID 539190598-(N-methylpiperazinyl)octylamine

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Hydrazine (aqueous solution at 35% by wt.) (0.15 ml; 1.6 mmoles) was added to 8-(N-methylpiperazinyl)octylphthalimide (285 mg; 0.8 mmoles) in methanol (5 ml) and the resulting solution was refluxed. Reaction times and process as per Example 1.

Workup

  1. temperaturethe resulting solution was refluxed
  2. customReaction times and process as per Example 1

Sources & evidence

ORD record
ord-4b307a7784294c938b96ea6205f0c702
Source dataset
uspto-grants-1994_04
Patent number
US05302593

Reaction notes

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