Hydrazine → 8-Pyrrolidinyloctylamine

HRID 1463822Notes

Reaction equation

HRID 1463822 reaction equation
[NH2:1]N.[N:3]1([CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15]C2C=CC=C3C(NC(=O)C=23)=O)[CH2:7][CH2:6][CH2:5][CH2:4]1>CO>[N:3]1([CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][NH2:1])[CH2:4][CH2:5][CH2:6][CH2:7]1

Participants

4

Reactant 2

HCID 9321HydrazineHCID 542934218-Pyrrolidinyloctylphthalimide

Product 1

HCID 199335008-Pyrrolidinyloctylamine

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Hydrazine (aqueous solution at 35% by wt.) (0.15 ml; 1.6 mmoles) was added to 8-pyrrolidinyloctylphthalimide (263 mg; 0.8 mmoles) in methanol (5 ml) and the resulting solution was refluxed. Reaction times and process as per Example 1.

Workup

  1. temperaturethe resulting solution was refluxed
  2. customReaction times and process as per Example 1

Sources & evidence

ORD record
ord-8b4d10a573ec41db9f7b3f9c763bc267
Source dataset
uspto-grants-1994_04
Patent number
US05302593

Reaction notes

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