Ethanol → HCID 19088488, compound

Participants

Reaction Steps

A solution of 3-(N-benzyl-N-methylamino)-3-methyl-butan-1-ol (6.9 g--see Preparation 10) in chloroform (20 ml) was added dropwise over 30 minutes to a solution of thionyl chloride (4.9 ml) in chloroform (20ml) at 0°. When the addition was complete, the mixture was stirred at room temperature for 18 hours. Ethanol (5 ml) was added and the mixture concentrated in vacuo to give an oil which was crystallised from ethyl acetate to give the title compound as a colourless powder, yield 2.62 g, m.p. 164°-166°.

Provenance & Evidence