HRID1463943

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID12761172

未命名化合物

结构：CN1C(=O)CC[C@@]2(C)C1=CC[C@H]1[C@@H]3CC[C@H](C(=O)O)[C@@]3(C)CC[C@@H]12

HCID22812150

未命名化合物

PRODUCTS

生成物

结构：CN1C(=O)CC[C@@]2(C)C1=CC[C@H]1[C@@H]3CC[C@H](C(=O)NC(C)(c4ccccc4)c4ccccc4)[C@@]3(C)CC[C@@H]12

HCID67750759

未命名化合物

收率 61%

PROCEDURE

实验过程

The title compound was prepared in a yield of 61% in a similar manner to that described in Example 2 by reacting 4-methyl-3-oxo-4-azaandrost-5-ene-17β-carboxylic acid (prepared as described in Preparation 5) and 1,1-diphenylethylamine.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-b827e3afc240457d94379a81e33bbb46
来源数据集: uspto-grants-1994_04
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05302621
来源说明: uspto-grants-1994_04

反应 SMILES

[CH3:1][N:2]1[C:19](=[O:20])[CH2:18][CH2:17][C@@:16]2([CH3:21])[C:3]1=[CH:4][CH2:5][C@@H:6]1[C@@H:15]2[CH2:14][CH2:13][C@@:11]2([CH3:12])[C@H:7]1[CH2:8][CH2:9][C@@H:10]2[C:22](O)=[O:23].[C:25]1([C:31]([NH2:39])([C:33]2[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=2)[CH3:32])[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1>>[C:25]1([C:31]([NH:39][C:22]([C@H:10]2[CH2:9][CH2:8][C@H:7]3[C@H:6]4[C@H:15]([CH2:14][CH2:13][C@:11]23[CH3:12])[C@:16]2([CH3:21])[C:3]([N:2]([CH3:1])[C:19](=[O:20])[CH2:18][CH2:17]2)=[CH:4][CH2:5]4)=[O:23])([C:33]2[CH:34]=[CH:35][CH:36]=[CH:37][CH:38]=2)[CH3:32])[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1