3-Oxo-4-aza-5-androstene-17beta-carboxylic acid → HCID 67750588, compound

HRID 1463955Notes

Reaction equation

HRID 1463955 reaction equation
[O:1]=[C:2]1[CH2:19][CH2:18][C@@:17]2([CH3:20])[C:4](=[CH:5][CH2:6][C@@H:7]3[C@@H:16]2[CH2:15][CH2:14][C@@:12]2([CH3:13])[C@H:8]3[CH2:9][CH2:10][C@@H:11]2[C:21](O)=[O:22])[NH:3]1.[S:24]1[CH:28]=[CH:27][CH:26]=[C:25]1[CH:29]([NH2:36])[CH2:30][C:31]1[S:32][CH:33]=[CH:34][CH:35]=1>>[S:24]1[CH:28]=[CH:27][CH:26]=[C:25]1[CH:29]([NH:36][C:21]([C@H:11]1[CH2:10][CH2:9][C@H:8]2[C@H:7]3[C@H:16]([CH2:15][CH2:14][C@:12]12[CH3:13])[C@:17]1([CH3:20])[C:4]([NH:3][C:2](=[O:1])[CH2:19][CH2:18]1)=[CH:5][CH2:6]3)=[O:22])[CH2:30][C:31]1[S:32][CH:33]=[CH:34][CH:35]=1

Participants

3

Reactant 2

HCID 4754473-Oxo-4-aza-5-androstene-17beta-carboxylic acidHCID 19088941HCID 19088941, compound

Product 1

HCID 67750588HCID 67750588, compoundYield 40%

Procedure

The title compound was prepared in a yield of 40% in a similar manner to that described in Example 1 by reacting 3-oxo-4-azaandrost-5-ene-17β-carboxylic acid and 1,2-di(2-thienyl)ethylamine.

Sources & evidence

ORD record
ord-2bb9e0620755481a8a7b6f1aa2807733
Source dataset
uspto-grants-1994_04
Patent number
US05302621

Reaction notes

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