HRID1463957

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID350041

1-(4-Methoxyphenyl)-1-phenylmethanamine

C14H15NO

结构：C[C@]12CC[C@H]3[C@@H](CC=C4NC(=O)CC[C@@]43C)[C@@H]1CC[C@@H]2C(=O)O

HCID475447

3-Oxo-4-aza-5-androstene-17beta-carboxylic acid

C19H27NO3

PRODUCTS

生成物

结构：COc1ccc(C(NC(=O)[C@H]2CC[C@H]3[C@@H]4CC=C5NC(=O)CC[C@]5(C)[C@H]4CC[C@]23C)c2ccccc2)cc1

HCID67750824

未命名化合物

收率 57%

PROCEDURE

实验过程

The title compound was prepared in a yield of 57% in a similar manner to that described in Example 1 by reacting 3-oxo-4-azaandrost-5-ene-17β-carboxylic acid and α-(4-methoxyphenyl)benzylamine.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-2391e00104c74f31a5201bd1ea9dc7b8
来源数据集: uspto-grants-1994_04
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05302621
来源说明: uspto-grants-1994_04

反应 SMILES

[O:1]=[C:2]1[CH2:19][CH2:18][C@@:17]2([CH3:20])[C:4](=[CH:5][CH2:6][C@@H:7]3[C@@H:16]2[CH2:15][CH2:14][C@@:12]2([CH3:13])[C@H:8]3[CH2:9][CH2:10][C@@H:11]2[C:21]([OH:23])=O)[NH:3]1.[CH3:24][O:25][C:26]1[CH:31]=[CH:30][C:29]([CH:32]([NH2:39])[C:33]2[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=2)=[CH:28][CH:27]=1>>[CH3:24][O:25][C:26]1[CH:27]=[CH:28][C:29]([CH:32]([NH:39][C:21]([C@H:11]2[CH2:10][CH2:9][C@H:8]3[C@H:7]4[C@H:16]([CH2:15][CH2:14][C@:12]23[CH3:13])[C@:17]2([CH3:20])[C:4]([NH:3][C:2](=[O:1])[CH2:19][CH2:18]2)=[CH:5][CH2:6]4)=[O:23])[C:33]2[CH:34]=[CH:35][CH:36]=[CH:37][CH:38]=2)=[CH:30][CH:31]=1