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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1463959Generated: October 26, 2026

3-Oxo-4-aza-5-androstene-17beta-carboxylic acid → N-[2-Phenyl-1-(2-thienyl)ethyl]-3-oxo-4-azaandrost-5-ene-17beta-carboxamide

https://huagongshe.com/reaction/1463959

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Oxo-4-aza-5-androstene-17beta-carboxylic acidHCID 475447—
Reactant2-Phenyl-1-(thiophen-2-yl)ethan-1-amineHCID 12751647—
ProductN-[2-Phenyl-1-(2-thienyl)ethyl]-3-oxo-4-azaandrost-5-ene-17beta-carboxamideHCID 6775097245%

Reaction Steps

The title compound was prepared in a yield of 45% in a similar manner to that described in Example 1 by reacting 3-oxo-4-azaandrost-5-ene-17β-carboxylic acid and 2-phenyl-1-(2-thienyl)ethylamine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05302621
Source datasetuspto-grants-1994_04
ORD IDord-599a7a408b684f72a0b7660bdd0bc40e
Source noteuspto-grants-1994_04