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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1463964Generated: October 25, 2026

2-(Thiophen-2-yl)propan-2-amine → N-[1-Methyl-1-(2-thienyl)ethyl]-4-methyl-3-oxo-4-azaandrost-5-ene-17beta-carboxamide

https://huagongshe.com/reaction/1463964

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Thiophen-2-yl)propan-2-amineHCID 45099—
Reactant4-Methyl-3-oxo-4-azaandrost-5-ene-17beta-carboxylic acidHCID 22812150—
ProductN-[1-Methyl-1-(2-thienyl)ethyl]-4-methyl-3-oxo-4-azaandrost-5-ene-17beta-carboxamideHCID 6775066750%

Reaction Steps

The title compound was prepared in a yield of 50% in a similar manner to that described in Example 2 by reacting 4-methyl-3-oxo-4-azaandrost-5-ene-17β-carboxylic acid (prepared as described in Preparation 5) and 1-methyl-1-(2-thienyl)ethylamine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05302621
Source datasetuspto-grants-1994_04
ORD IDord-759b35d22a3b41b88d63b25c78671dde
Source noteuspto-grants-1994_04